Hazardous Materials Design Issues

Facilities shall be designed so use of a respirator is not required for normal operations.


UC Practice

29 CFR 1910.134(a) (1)

NCRP Report No. 127 Section 4.5


General ventilation systems should be designed, such that in the event of an incident, they can be shut down and isolated to contain radioactivity, biological aerosols, or hazardous chemicals.


UC Practice

NUREG 1556, Vol. 7, Appendix L


A pressure differential system should be used to control the flow of airborne contamination. The flow should always be from clean areas to contaminated areas.  Similar areas may not always require the same ventilation characteristics so careful consultation with health and safety and users shall be accomplished.


UC Practice

NCRP Report, No. 127, Section 4.5


An area for spill or emergency response equipment shall be located on each floor. This area shall be a minimum of 50 square feet (4.6 m2), with an increase in the size at the rate of 5 square feet (0.46 m2) per 1,000 square feet (93 m2) in excess of 10,000 square feet (929 m2), and shall have at least two standard electrical outlets and overhead lighting.


Prudent Practices in the Laboratory 5.C.11.5 & 5.C.11.6

24 CCR Part 2 307.2.12 (applies to H occupancies)


Lockable doors, lockable cabinets, etc. shall be provided to secure specifically regulated materials such as controlled substances (regulated by the Drug Enforcement Administration), select agents (regulated by Centers for Disease Control [CDC]), and radioactive materials (regulated by the Radiologic Health Branch California Department of Public Health), where applicable.


17 CCR, California Radiation Control Regulations

Controlled Substances Act, Section 803

State of California, Department of Health Services, Radiologic Health Branch RH 2010 4/90


Sufficient space or facilities should be provided so materials with unique physical or particularly hazardous properties are stored safely.  Materials which in combination with other substances may cause a fire or explosion, or liberate a flammable or poisonous gas, are kept separate. Separate space or facilities can include storage cabinets with partitions, acid cabinets, flammable cabinets, gas cabinets, etc.


When designing shelves and shelf spacing, it is important to include enough space (height and depth) for secondary containers and to be sure shelving is easily adjustable.


24 CCR 9 (CFC) 8001.9.8

NFPA 45, Chapter 9.2